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Giovanni Natile Selected Research

Diamines

6/2022Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration.
8/2016Encapsulation of lipophilic kiteplatin Pt(iv) prodrugs in PLGA-PEG micelles.
4/2008Conformer distribution in (cis-1,4-DACH)bis(guanosine-5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin.

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Giovanni Natile Research Topics

Disease

45Neoplasms (Cancer)
06/2022 - 11/2003
6Colorectal Neoplasms (Colorectal Cancer)
06/2022 - 08/2012
5Colonic Neoplasms (Colon Cancer)
08/2016 - 08/2012
4Hepatolenticular Degeneration (Wilson's Disease)
01/2019 - 08/2009
4Ovarian Neoplasms (Ovarian Cancer)
09/2015 - 08/2004
3Neurodegenerative Diseases (Neurodegenerative Disease)
11/2014 - 09/2009
3Glioma (Gliomas)
11/2014 - 07/2010
3Neoplasm Metastasis (Metastasis)
08/2012 - 08/2007
2Bites and Stings (Sting)
02/2015 - 04/2008
1Lewis Lung Carcinoma
06/2022
1Lymphoma (Lymphomas)
11/2021
1Sarcoma (Soft Tissue Sarcoma)
11/2021
1Necrosis
06/2021
1Uterine Cervical Neoplasms (Cancer of the Cervix)
03/2020
1Carcinoma (Carcinomatosis)
10/2019
1Neuroblastoma
11/2018
1Ototoxicity
01/2017
1Glioblastoma (Glioblastoma Multiforme)
06/2016
1Breast Neoplasms (Breast Cancer)
06/2016
1Rectal Neoplasms (Rectal Cancer)
01/2016
1Hepatocellular Carcinoma (Hepatoma)
08/2012
1Lung Neoplasms (Lung Cancer)
01/2012
1Osteosarcoma (Osteogenic Sarcoma)
01/2012
1Metabolic Bone Diseases (Osteopenia)
04/2011
1Mesothelioma
04/2011
1Malignant Mesothelioma
04/2011
1Hepatitis
02/2011
1Prion Diseases (Transmissible Spongiform Encephalopathies)
09/2009
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
09/2009
1Decompression Sickness (Bends)
12/2007
1Genomic Instability
07/2006

Drug/Important Bio-Agent (IBA)

30Cisplatin (Platino)FDA LinkGeneric
06/2022 - 11/2003
21LigandsIBA
06/2022 - 11/2003
19PlatinumIBA
11/2021 - 08/2004
14Oxaliplatin (Eloxatin)FDA LinkGeneric
06/2022 - 12/2007
10DNA (Deoxyribonucleic Acid)IBA
01/2019 - 11/2003
8Pharmaceutical PreparationsIBA
06/2022 - 11/2003
8platinum(II)(1,4- diazacycloheptane)dichlorideIBA
06/2022 - 09/2014
7Proteins (Proteins, Gene)FDA Link
01/2019 - 11/2003
6transplatinIBA
01/2015 - 11/2003
51,2-cyclohexanediamine (dach)IBA
06/2022 - 04/2008
4Platinum Compounds (Compounds, Platinum)IBA
12/2009 - 11/2003
3Benzoates (Benzoate)IBA
06/2022 - 01/2016
3DiaminesIBA
06/2022 - 04/2008
3ProdrugsIBA
06/2022 - 09/2015
3Glutathione (Reduced Glutathione)IBA
09/2019 - 11/2006
3Antineoplastic Agents (Antineoplastics)IBA
09/2014 - 08/2012
2Adenosine Triphosphatases (ATPase)IBA
01/2019 - 06/2018
2CopperIBA
06/2018 - 01/2018
2diphosphoric acid (pyrophosphoric acid)IBA
10/2017 - 04/2011
2NitrogenIBA
02/2015 - 04/2011
2AminesIBA
09/2014 - 01/2007
2Diphosphonates (Bisphosphonates)IBA
08/2012 - 04/2011
2Biological ProductsIBA
12/2009 - 07/2007
11,4-diaminocyclohexaneIBA
06/2021
1cyclohexeneIBA
03/2020
1Glutathione Disulfide (GSSG)FDA LinkGeneric
09/2019
1P-type ATPasesIBA
01/2019
1HMGB ProteinsIBA
12/2018
1neocuproineIBA
11/2018
1PhenanthrolinesIBA
11/2018
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
05/2018
1Chelating AgentsIBA
01/2018
1tetrathiomolybdate (ammonium tetrathiomolybdate)IBA
01/2018
1Cytotoxins (Cytolysins)IBA
02/2017
1Acetates (Acetic Acid Esters)FDA Link
06/2016
1Oleic Acid (Oleate)IBA
01/2016
1AmidesIBA
01/2016
1Biomarkers (Surrogate Marker)IBA
12/2015
1Protons (Proton)IBA
02/2015
1Coordination ComplexesIBA
11/2014
1Growth InhibitorsIBA
06/2014
1ApatitesIBA
01/2012
1SaltsIBA
02/2011
1GABA-A Receptors (GABA(A) Receptor)IBA
07/2010
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
02/2010
1DNA AdductsIBA
02/2010
1EnzymesIBA
12/2009
1Liposomes (Liposome)IBA
09/2009
1IonsIBA
09/2009
11-palmitoyl-2-oleoylphosphatidylcholineIBA
09/2009
1UbiquitinIBA
09/2009
1Proteasome Endopeptidase Complex (Proteasome)IBA
09/2009
1MetalsIBA
09/2009
1SolutionsIBA
08/2009
1DNA Polymerase I (Klenow Fragment)IBA
12/2007
1Amantadine (Aman)FDA LinkGeneric
11/2006
1SulfurIBA
11/2006
1MetallothioneinIBA
11/2006
1(PtCl(2)(CH(3)COO)(2)- (NH(3))(1- adamantylamine))IBA
11/2006
1carboxyl radical (COO-)IBA
11/2006
1EDDA (NiEDDA)IBA
08/2004
1ChloridesIBA
08/2004
1HalogensIBA
08/2004

Therapy/Procedure

3Therapeutics
08/2007 - 11/2006
2Drug Therapy (Chemotherapy)
06/2018 - 08/2012
1Intraperitoneal Injections
06/2022
1Oral Administration
06/2022